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The principal cytochrome P450 isoenzyme included seems for being CYP2E1, with CYP1A2 and CYP3A4 as supplemental pathways. Roughly 85% of the oral dose seems inside the urine in just 24 hours of administration, most because the glucuronide conjugate, with compact quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity informa